Yes, blood sugar levels can affect hot flashes in postmenopausal women. Fluctuations in blood sugar can lead to changes in hormone levels and overall body temperature regulation, potentially exacerbating hot flashes. For instance, high blood sugar levels can cause inflammation and hormonal imbalances, which may increase the frequency and intensity of hot flashes. Maintaining stable blood sugar levels through a balanced diet, regular exercise, and proper hydration can help manage these symptoms. If hot flashes are severe or persistent, consulting a healthcare provider is advisable for personalized advice and treatment options.